This Saint Anthony was a Spanish born Jesuit who went to Cuba to be the archbishop in the middle of the nineteenth century. Tough place, Cuba. Resistance to his administration was fierce, including an (unsuccessful) assassination attempt. He resigned the post in 1857 and returned to Spain to be the confessor to Queen Isabella II. While there, he set up a science laboratory, a natural history museum, and a music and language school.
Tough place, Spain. Following the Revolution of 1868, he followed his Queen into exile, dying a couple years later in a Cistercian monastery.